Our paper on the catalytic mechanism and conformational dynamics of guinea pig l-asparaginase type 1 has just been published in ACS Catalysis!

Our paper identifies the catalytic mechanism, key residues and the role of the electric field and loop dynamics of the substrate binding that guide rational enzyme engineering. You can check out the full article here: https://pubs.acs.org/doi/10.1021/acscatal.4c07791